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Identification of a Novel Inhibitor against Middle East Respiratory Syndrome Coronavirus

The Middle East respiratory syndrome coronavirus (MERS-CoV) was first isolated in 2012, and circulated worldwide with high mortality. The continual outbreaks of MERS-CoV highlight the importance of developing antiviral therapeutics. Here, we rationally designed a novel fusion inhibitor named MERS-fi...

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Principais autores: Yaping Sun, Huaidong Zhang, Jian Shi, Zhe Zhang, Rui Gong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2017-09-01
Serier:Viruses
Fag:
MERS-CoV
fusion inhibitor
six-helix bundle
heptad repeat
five-helix bundle
Online adgang:https://www.mdpi.com/1999-4915/9/9/255
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