Synthesis and Anticancer Evaluation of 4-Chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol Analogues: An Insight into Experimental and Theoretical Studies

We report herein the synthesis, docking studies and biological evaluation of a series of new 4-chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol analogues (<b>6a-h</b>). The new compounds were designed based on the oxadiazole-linked aryl core of tubulin inhibitors of IMC-038525 and IMC-094332, pre...

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Bibliografski detalji

Glavni autori:	Obaid Afzal, Amena Ali, Abuzer Ali, Abdulmalik Saleh Alfawaz Altamimi, Manal A. Alossaimi, Md Afroz Bakht, Salahuddin, Mubarak A. Alamri, Md. Faiyaz Ahsan, Mohamed Jawed Ahsan
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2023-08-01
Serija:	Molecules
Teme:	anticancer antibacterial DNA gyrase molecular docking 1,3,4-oxadiazole tubulin
Online pristup:	https://www.mdpi.com/1420-3049/28/16/6086
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