Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn’s disease

Abstract Background Crohn’s disease (CD) is associated with changes in the microbiota, and murine models of CD-like ileo-colonic inflammation depend on the presence of microbial triggers. Increased abundance of unknown Clostridiales and the microscopic detection of filamentous structures close to th...

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Hlavní autoři:	Amira Metwaly, Jelena Jovic, Nadine Waldschmitt, Sevana Khaloian, Helena Heimes, Deborah Häcker, Mohamed Ahmed, Nassim Hammoudi, Lionel Le Bourhis, Aida Mayorgas, Kolja Siebert, Marijana Basic, Tobias Schwerd, Matthieu Allez, Julian Panes, Azucena Salas, André Bleich, Sebastian Zeissig, Pamela Schnupf, Fabio Cominelli, Dirk Haller
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-03-01
Edice:	Microbiome
Témata:	Crohn’s disease Segmented filamentous bacteria Purified diet Tnf ΔARE mice Inflammation Pathobiont
On-line přístup:	https://doi.org/10.1186/s40168-023-01508-y
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