Identification of specific susceptibility loci for the early-onset colorectal cancer

Abstract Background The incidence of early-onset colorectal cancer (EOCRC; patients < 50 years old) has been rising rapidly, whereas the EOCRC genetic susceptibility remains incompletely investigated. Here, we aimed to systematically identify specific susceptible genetic variants for EOCRC. Methods...

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Autori principali:	Haoxue Wang, Yimin Cai, Meng Jin, Chao Qun Huang, Caibo Ning, Siyuan Niu, Linyun Fan, Bin Li, Ming Zhang, Zequn Lu, Xuesi Dong, Zilin Luo, Rong Zhong, Heng Li, Ying Zhu, Xiaoping Miao, Xiaojun Yang, Jiang Chang, Ni Li, Jianbo Tian
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-03-01
Serie:	Genome Medicine
Soggetti:	GWAS Early-onset CRC Genetic variants PRS POLA2
Accesso online:	https://doi.org/10.1186/s13073-023-01163-w
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