ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation

Prdm14 is a sequence-specific transcriptional regulator of embryonic stem cell (ESC) pluripotency and primordial germ cell (PGC) formation. It exerts its function, at least in part, through repressing genes associated with epigenetic modification and cell differentiation. Here, we show that this rep...

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主要な著者:	Nataliya Nady, Ankit Gupta, Ziyang Ma, Tomek Swigut, Akiko Koide, Shohei Koide, Joanna Wysocka
フォーマット:	Artigo
言語:	Inglês
出版事項:	eLife Sciences Publications Ltd 2015-11-01
シリーズ:	eLife
主題:	epigenetic primordial Germ Cells embryonic stem cell genomic monobody X-ray crystallography
オンライン･アクセス:	https://elifesciences.org/articles/10150
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