Bromodomain and Extra-Terminal Protein Inhibitors: Biologic Insights and Therapeutic Potential in Pediatric Brain Tumors

Pediatric brain tumors have surpassed leukemia as the leading cause of cancer-related death in children. Several landmark studies from the last two decades have shown that many pediatric brain tumors are driven by epigenetic dysregulation within specific developmental contexts. One of the major dete...

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Detalhes bibliográficos

Principais autores:	Andrew Groves, Jessica Clymer, Mariella G. Filbin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-05-01
coleção:	Pharmaceuticals
Assuntos:	BET inhibitor epigenetics pediatric brain tumors diffuse intrinsic pontine glioma medulloblastoma ependymoma
Acesso em linha:	https://www.mdpi.com/1424-8247/15/6/665
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