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Population genomics of intrapatient HIV-1 evolution

Many microbial populations rapidly adapt to changing environments with multiple variants competing for survival. To quantify such complex evolutionary dynamics in vivo, time resolved and genome wide data including rare variants are essential. We performed whole-genome deep sequencing of HIV-1 popula...

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Bibliographic Details
Main Authors: Fabio Zanini, Johanna Brodin, Lina Thebo, Christa Lanz, Göran Bratt, Jan Albert, Richard A Neher
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
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Online Access:https://elifesciences.org/articles/11282
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