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Immuno-Modulatory Effects of Intervertebral Disc Cells

Low back pain is a highly prevalent, chronic, and costly medical condition predominantly triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and biochemical changes in intervertebral discs (IVD) that prompt a pathologic shift from an anabolic to catabolic state, af...

Celý popis

Uloženo v:
Hlavní autoři: Paola Bermudez-Lekerika, Katherine B. Crump, Sofia Tseranidou, Andrea Nüesch, Exarchos Kanelis, Ahmad Alminnawi, Laura Baumgartner, Estefano Muñoz-Moya, Roger Compte, Francesco Gualdi, Leonidas G. Alexopoulos, Liesbet Geris, Karin Wuertz-Kozak, Christine L. Le Maitre, Jérôme Noailly, Benjamin Gantenbein
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-06-01
Edice:Frontiers in Cell and Developmental Biology
Témata:
intervertebral disc degeneration
low back pain
inflammation
catabolism
immune-privileged microenvironment
GWAS
On-line přístup:https://www.frontiersin.org/articles/10.3389/fcell.2022.924692/full
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