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Single-cell transcriptome profiling reveals immunological fitness of HIV long-term non-progressors

ABSTRACT Long-term non-progressors (LTNPs) represent a valuable model to investigate immunological features associated with non-progression in chronic HIV infection. In this study, single-cell RNA sequencing was performed on peripheral blood mononuclear cells obtained from 12 individuals, including...

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Principais autores: Minjuan Shi, Rongfeng Chen, Tongjin Wu, Yu Liao, Tongxue Qin, Ziyu Wen, Junqi Liu, Xiu Chen, Beibei Lu, Chunxing Yi, Li Ye, Hao Liang, Caijun Sun, Junjun Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2025-12-01
coleção:Journal of Virology
Assuntos:
HIV reservoirs
long-term non-progressors
scRNA-seq
HIV cure
Acesso em linha:https://journals.asm.org/doi/10.1128/jvi.01597-25
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