TET1 displays catalytic and non-catalytic functions in the adult mouse cortex
TET1/2/3 dioxygenases iteratively demethylate 5-methylcytosine, beginning with the formation of 5-hydroxymethylcytosine (5hmC). The post-mitotic brain maintains higher levels of 5hmC than most peripheral tissues, and TET1 ablation studies have underscored the critical role of TET1 in brain physiolog...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis Group
2024-12-01
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| Colección: | Epigenetics |
| Materias: | |
| Acceso en línea: | https://www.tandfonline.com/doi/10.1080/15592294.2024.2374979 |
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