The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding

Lectin-like oxidized LDL (ox-LDL) receptor-1 (LOX-1) is a type-II transmembrane protein that belongs to the C-type lectin family of molecules. LOX-1 acts as a cell surface endocytosis receptor and mediates the recognition and internalization of ox-LDL by vascular endothelial cells. Internalization o...

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Autori principali:	Omar L. Francone, Meihua Tu, Lori J. Royer, Jian Zhu, Kimberly Stevens, Joseph J. Oleynek, Zhiwu Lin, Lorraine Shelley, Thomas Sand, Yi Luo, Christopher D. Kane
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2009-03-01
Serie:	Journal of Lipid Research
Soggetti:	lipoprotein oxidation scavenger receptors endothelial cells
Accesso online:	http://www.sciencedirect.com/science/article/pii/S002222752030897X
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