Genetic Determinants of Body Mass Index and Fasting Glucose Are Mediators of Grade 1 Diastolic Dysfunction

Background Early (grade 1) cardiac left ventricular diastolic dysfunction (G1DD) increases the risk for heart failure with preserved ejection fraction and may improve with aggressive risk factor modification. Type 2 diabetes, obesity, hypertension, and coronary heart disease are associated with incr...

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Podrobná bibliografie

Hlavní autoři:	Nataraja Sarma Vaitinadin, Mingjian Shi, Christian M. Shaffer, Eric Farber‐Eger, Brandon D. Lowery, Vineet Agrawal, Deepak K. Gupta, Dan M. Roden, Quinn S. Wells, Jonathan D. Mosley
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2022-06-01
Edice:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Témata:	body mass index diastolic dysfunction fasting glucose genetic epidemiology Mendelian randomization
On-line přístup:	https://www.ahajournals.org/doi/10.1161/JAHA.122.025578
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