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Inhibitory effects of safranal on laser-induced choroidal neovascularization and human choroidal microvascular endothelial cells and related pathways analyzed with transcriptome sequencing

AIM: To determine the effects of safranal on choroidal neovascularization (CNV) and oxidative stress damage of human choroidal microvascular endothelial cells (HCVECs) and its possible mechanisms. METHODS: Forty-five rats were used as a laser-induced CNV model for testing the efficacy and safety of...

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Principais autores: Qin-Xiao, Yao-Yao Sun, Zhan-Jun Lu, Tian-Zi Zhang, Shan-Shan Li, Ting Hua, Suriguga, Wen-Lin Chen, Lin-Lin Ran, Wen-Zhen Yu, Fei Yang, Burenbatu
Format: Artigo
Sprog:Inglês
Udgivet: Press of International Journal of Ophthalmology (IJO PRESS) 2021-07-01
Serier:International Journal of Ophthalmology
Fag:
choroidal neovascularization
safranal
human choroidal microvascular endothelial cells
oxidative stress
transcriptomics
Online adgang:http://ies.ijo.cn/en_publish/2021/7/20210704.pdf
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