Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia.

DNA damage can activate the oncosuppressor protein ataxia telangiectasia mutated (ATM), which phosphorylates the histone H2AX within characteristic DNA damage foci. Here, we show that ATM undergoes an activating phosphorylation in syncytia elicited by the envelope glycoprotein complex (Env) of human...

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Үндсэн зохиолчид:	Jean-Luc Perfettini, Roberta Nardacci, Mehdi Bourouba, Frédéric Subra, Laurent Gros, Claire Séror, Gwenola Manic, Filippo Rosselli, Alessandra Amendola, Peggy Masdehors, Luciana Chessa, Giuseppe Novelli, David M Ojcius, Jan Konrad Siwicki, Magdalena Chechlinska, Christian Auclair, José R Regueiro, Hugues de Thé, Marie-Lise Gougeon, Mauro Piacentini, Guido Kroemer
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2008-06-01
Цуврал:	PLoS ONE
Онлайн хандалт:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18560558/pdf/?tool=EBI
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!