An Integrated Pipeline for Combining in vitro Data and Mathematical Models Using a Bayesian Parameter Inference Approach to Characterize Spatio-temporal Chemokine Gradient Formation

All protective and pathogenic immune and inflammatory responses rely heavily on leukocyte migration and localization. Chemokines are secreted chemoattractants that orchestrate the positioning and migration of leukocytes through concentration gradients. The mechanisms underlying chemokine gradient es...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Dimitris I. Kalogiros, Matthew J. Russell, Willy V. Bonneuil, Jennifer Frattolin, Daniel Watson, James E. Moore, Theodore Kypraios, Bindi S. Brook
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-10-01
coleção:	Frontiers in Immunology
Assuntos:	chemokine transport dynamics microfluidic device model validation Bayesian parameter inference sequential Bayesian updating MCMC methods
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01986/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!