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Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in Trypanosoma cruzi populations

Trypanosoma cruzi, the causative agent of Chagas disease, presents a major public health challenge in Central and South America, affecting approximately 8 million people and placing millions more at risk. The T. cruzi life cycle includes transitions between epimastigote, metacyclic trypomastigote, a...

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Principais autores: Lucas Inchausti, Lucia Bilbao, Vanina A Campo, Joaquín Garat, José Sotelo-Silveira, Gabriel Rinaldi, Virginia M Howick, Maria A Duhagon, Javier G De Gaudenzi, Pablo Smircich
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2026-04-01
coleção:eLife
Assuntos:
Trypanosoma cruzi
transcriptional heterogeneity
trans-sialidase-like superfamily
host-pathogen interactions
Single-cell RNA-seq
Acesso em linha:https://elifesciences.org/articles/105822
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