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Mutation and Expression of the DCC Gene in Human Lung Cancer

Chromosome 18q is frequently deleted in lung cancers, a common region of 18q deletions was mapped to chromosome 18g21. Since the DCC candidate tumor suppressor gene has been mapped in this region, mutation and expression of the DCC gene were examined in 46 lung cancer cell lines, consisting of 14 sm...

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Hlavní autoři: Takashi Kohno, Takako Sato, Satoshi Takakura, Kimiko Takei, Kaoru Inoue, Michiho Nishioka, Jun Yokota
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2000-07-01
Edice:Neoplasia: An International Journal for Oncology Research
Témata:
DCC
lung cancer
chromosome 18
tumor suppressor gene
mutation
On-line přístup:http://www.sciencedirect.com/science/article/pii/S1476558600800020
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