Long-term low-dose aspirin promotes laser-induced choroidal neovascularization through suppressing TSP-1 expression

PurposeTo investigate the impact of low-dose, long-term aspirin use on neovascular age-related macular degeneration (nAMD).MethodsAdult C57BL/6J or Thbs-1–/– mice were treated with daily aspirin (1.25 mg/kg) for 8 weeks before being subjected to laser-induced choroidal neovascularization (CNV). The...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Caijiao Yi, Chang Luo, Jiawu Zhao, Christophe Roubeix, Judith Lechner, Rosana Penalva, Nan Yang, Jian Liu, Qichang Wang, Usha Chakravarthy, Florian Sennlaub, Mei Chen, Heping Xu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-12-01
Edice:	Frontiers in Cellular Neuroscience
Témata:	age-related macular degeneration angiogenesis inflammation aspirin macrophages
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fncel.2025.1716229/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!