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Identification of coordinately regulated microRNA-gene networks that differ in baboons discordant for LDL-cholesterol.

<h4>Rationale</h4>Plasma low-density lipoprotein cholesterol (plasma LDL-C), vascular endothelial cells and peripheral blood mononuclear cells (PBMCs), particularly monocytes, play key roles in initiating atherosclerosis, the primary cause of cardiovascular disease (CVD). Although the mechanisms und...

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Principais autores: Genesio M Karere, Jeremy P Glenn, Shifra Birnbaum, Roy Garcia, John L VandeBerg, Laura A Cox
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0213494
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