Regulating the regulators via targeting CD38 in the tumor microenvironment

The immunosuppressive tumor microenvironment (TME) remains a major barrier to effective cancer immunotherapy. Among the central regulators of immune suppression, CD38, a multifunctional ectoenzyme and surface glycoprotein, has emerged as a pivotal orchestrator. CD38 is abundantly expressed on regula...

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Bibliografiske detaljer

Principais autores:	Navnita Dutta, Nabanita Halder, Eduardo Nunes Chini, Sungjune Kim, Alak Manna
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2026-02-01
Serier:	Frontiers in Immunology
Fag:	Breg CD38 metabolism NAD tumor micro environment (TME)
Online adgang:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1745988/full
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