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TAZ Controls <i>Helicobacter pylori</i>-Induced Epithelial–Mesenchymal Transition and Cancer Stem Cell-Like Invasive and Tumorigenic Properties

<i>Helicobacter pylori</i> infection, the main risk factor for gastric cancer (GC), leads to an epithelial–mesenchymal transition (EMT) of gastric epithelium contributing to gastric cancer stem cell (CSC) emergence. The Hippo pathway effectors yes-associated protein (YAP) and transcriptional co-acti...

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Principais autores: Camille Tiffon, Julie Giraud, Silvia Elena Molina-Castro, Sara Peru, Lornella Seeneevassen, Elodie Sifré, Cathy Staedel, Emilie Bessède, Pierre Dubus, Francis Mégraud, Philippe Lehours, Océane C.B. Martin, Christine Varon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-06-01
coleção:Cells
Assuntos:
gastric cancer
<i>Helicobacter pylori</i>
hippo pathway
ZEB1
epithelial–mesenchymal transition
TAZ
Acesso em linha:https://www.mdpi.com/2073-4409/9/6/1462
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