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Assessing immune hepatotoxicity of troglitazone with a versatile liver-immune-microphysiological-system

Drug-induced liver injury is a prevalent adverse event associated with pharmaceutical agents. More significantly, there are certain drugs that present severe hepatotoxicity only during the clinical phase, consequently leading to the termination of drug development during clinical trials or the withd...

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Principais autores: Quanfeng Deng, Youlong Yang, Yuangui Liu, Mengting Zou, Guiyuan Huang, Shiqi Yang, Lingyu Li, Yueyang Qu, Yong Luo, Xiuli Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-05-01
coleção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2024.1335836/full
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