Protective effects of sinensetin on intestinal barrier damage induced by lipopolysaccharide in mice through TLR4/NLRP3/GSDMD pathway

Recent studies have increasingly indicated that sinensetin, a dietary-derived natural compound and key component of orange peel, can alleviate intestinal damage induced by cisplatin. In this study, we established a mouse model and utilized a Caco-2 cell system to investigate the effects of sinenseti...

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Autores principales:	Zhuoqun Meng, Qin Zhang, Ranran Zhang, Guirong Liu, Wenliang Xiang, Yang He, Qing Zhang, Jie Tang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2026-03-01
Colección:	Journal of Agriculture and Food Research
Materias:	Sinensetin Pyroptosis Intestinal barrier damage The TLR4/NLRP3/GSDMD pathway
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2666154325009652
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