Enhancing the Outcome of Crystallographic Fragment Screening by Choosing the Optimal Protein Crystal Form

Improving health and quality of life in our society is a key focus of drug development. Methods for drug discovery are being optimized in multiple ways to reduce costs and timelines. Crystallographic fragment screening (CFS) is increasingly being employed as an early screening method in drug discove...

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Bibliografske podrobnosti

Principais autores:	Tatjana Barthel, Jan Wollenhaupt, Laila S. Benz, Patrick Reinke, Linlin Zhang, Melanie Oelker, Frank Lennartz, Helena Taberman, Uwe Mueller, Alke Meents, Rolf Hilgenfeld, Manfred S. Weiss
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley-VCH 2026-03-01
Serija:	Small Science
Teme:	crystal form crystal soaking crystallographic fragment screening drug discovery main protease SARS‐CoV‐2
Online dostop:	https://doi.org/10.1002/smsc.202500484
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