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Unravelling the role of bilirubin metabolism in gallstone formation: a genetic and metabolic perspective

Abstract Gallstone disease is a widespread health issue driven by genetic, metabolic, and environmental factors. Among its types, pigment stones, primarily composed of bilirubin, arise due to disruptions in bilirubin metabolism. Heme degradation produces biliverdin, which is reduced to unconjugated...

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Hauptverfasser: Jashwanth Balu, Sanjana Murali, Pradeep Narahari Ram, R B Devi Krishna, Nandini Krishnamurthy, Shanthi Vijayaraghavan, Rajeshkumar Shanmugam, Andrea Mary Francis
Format: Artigo
Sprache:Inglês
Veröffentlicht: SpringerOpen 2026-01-01
Schriftenreihe:Egyptian Liver Journal
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Online-Zugang:https://doi.org/10.1186/s43066-026-00496-6
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