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Spectroscopic studies of the iron and manganese reconstituted tyrosyl radical in Bacillus cereus ribonucleotide reductase R2 protein.

Ribonucleotide reductase (RNR) catalyzes the rate limiting step in DNA synthesis where ribonucleotides are reduced to the corresponding deoxyribonucleotides. Class Ib RNRs consist of two homodimeric subunits: R1E, which houses the active site; and R2F, which contains a metallo cofactor and a tyrosyl...

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Autori principali: Ane B Tomter, Giorgio Zoppellaro, Caleb B Bell, Anne-Laure Barra, Niels H Andersen, Edward I Solomon, K Kristoffer Andersson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS ONE
Accesso online:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22432022/?tool=EBI
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