The role of peripheral β-amyloid in insulin resistance, insulin secretion, and prediabetes: in vitro and population-based studies

BackgroundPrevious experimental studies have shown that mice overexpressing amyloid precursor protein, in which β-amyloid (Aβ) is overproduced, exhibit peripheral insulin resistance, pancreatic impairment, and hyperglycemia. We aimed to explore the effects of Aβ on insulin action and insulin secreti...

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Автори:	Zihui Xu, Juan Chen, Pei Wang, Linyan Li, Shan Hu, Hongjie Liu, Yue Huang, Xiaoxing Mo, Hong Yan, Zhilei Shan, Di Wang, Jian Xu, Liegang Liu, Xiaobo Peng
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2023-07-01
Серія:	Frontiers in Endocrinology
Предмети:	peripheral β-amyloid in vitro study insulin resistance insulin secretion prediabetes population-based study
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1195658/full
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