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Phosphatase of Regenerating Liver-1 (PRL-1) Regulates Actin Dynamics During Immunological Synapse Assembly and T Cell Effector Function

The regulatory role of most dual specific phosphatases during T cell activation remains unknown. Here, we have studied the expression and function of phosphatases of regenerating liver (PRLs: PRL-1, PRL-2, and PRL-3) during T cell activation, as well as, the dynamic delivery of PRL-1 to the Immunolo...

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Principais autores: Patricia Castro-Sánchez, Rocío Ramirez-Munoz, Noa B. Martín-Cófreces, Oscar Aguilar-Sopeña, Sergio Alegre-Gomez, Sara Hernández-Pérez, Raquel Reyes, Qi Zeng, Carlos Cabañas, Francisco Sánchez-Madrid, Pedro Roda-Navarro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-11-01
coleção:Frontiers in Immunology
Assuntos:
T cell immune response
immunological synapse
phosphatases of regenerating liver
actin cytoskeleton
IL-2
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2018.02655/full
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