Effector Tc17 cells resist shift from OXPHOS to aerobic glycolysis

IL-17A-expressing lymphocytes, including Tc17 cells, are instrumental in immunity, immunopathology, and autoimmunity. We have previously shown that experimental attenuated live fungal vaccine-induced Tc17 cells are stable, long-lived without plasticity, and necessary to mediate sterilizing immunity...

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Podrobná bibliografie

Hlavní autoři:	Reni John, Srinivasu Mudalagiriyappa, Nagabhushan Chandrashekar, Som G. Nanjappa
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-05-01
Edice:	Frontiers in Immunology
Témata:	CD8+ T cell Tc17 cell glycolysis OXPHOS T cell activation antifungal
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1571221/full
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