Chalcone-Derived Lactones: Synthesis, Whole-Cell Biotransformation, and Evaluation of Their Antibacterial and Antifungal Activity

Four compounds with lactone moiety were synthesized from chalcone <b>1</b> in three- or four-step synthesis. γ-Bromo-δ-lactone <b>5</b> was the only product of bromolactonization of acid <b>4</b> whereas bromolactonization of ester <b>3</b>, apart from lactone <b>5</b> also afforded its isomer <b>6<...

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Váldodahkkit:	Witold Gładkowski, Monika Siepka, Barbara Żarowska, Agata Białońska, Barbara Gawdzik, Mariusz Urbaniak, Czesław Wawrzeńczyk
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	MDPI AG 2023-04-01
Ráidu:	Molecules
Fáttát:	chalcone bromolactonization hydroxylactones microbial dehalogenation translactonization antibacterial activity
Liŋkkat:	https://www.mdpi.com/1420-3049/28/9/3800
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