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Soluble RAGE further stratifies risk of coronary artery and end-stage kidney disease in high-risk individuals with type 1 diabetes and treatment-resistant hypertension

Abstract Background Soluble receptor for advanced glycation end-products (sRAGE) modulates RAGE-mediated inflammation and oxidative stress. We investigated if sRAGE stratifies cardiovascular and kidney disease risk in individuals with type 1 diabetes and baseline treatment-resistant hypertension (TR...

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Principais autores: Krishna Adeshara, Raija Lithovius, Stefan Mutter, Valma Harjutsalo, Markku Lehto, Per-Henrik Groop, Niina Sandholm, the FinnDiane Study Group
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-12-01
coleção:Cardiovascular Diabetology
Assuntos:
Soluble RAGE
Treatment-resistant hypertension
Coronary artery disease
Kidney disease
Type 1 diabetes
Acesso em linha:https://doi.org/10.1186/s12933-025-03017-8
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