Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies

Summary: In cystic fibrosis (CF) airways, Pseudomonas aeruginosa forms cellular aggregates called biofilms that are thought to contribute to chronic infection. To form aggregates, P. aeruginosa can use different mechanisms, each with its own pathogenic implications. However, how they form in vivo is...

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Principais autores:	Laura K. Jennings, Julia E. Dreifus, Courtney Reichhardt, Kelly M. Storek, Patrick R. Secor, Daniel J. Wozniak, Katherine B. Hisert, Matthew R. Parsek
格式:	Artigo
语言:	Inglês
出版:	Elsevier 2021-02-01
丛编:	Cell Reports
主题:	Pseudomonas aeruginosa biofilm matrix IHC exopolysaccharide Psl Pel cystic fibrosis
在线阅读:	http://www.sciencedirect.com/science/article/pii/S2211124721000954
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