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Positional weight matrices have sufficient prediction power for analysis of noncoding variants [version 2; peer review: 2 approved]

The position weight matrix, also called the position-specific scoring matrix, is the commonly accepted model to quantify the specificity of transcription factor binding to DNA. Position weight matrices are used in thousands of projects and software tools in regulatory genomics, including computation...

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Autors principals: Sergey Abramov, Alexandr Boytsov, Vsevolod J. Makeev, Ivan V. Kulakovskiy
Format: Artigo
Idioma:Inglês
Publicat: F1000 Research Ltd 2022-06-01
Col·lecció:F1000Research
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Accés en línia:https://f1000research.com/articles/11-33/v2
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