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9,10-Bis[(4-(2-hydroxyethyl)piperazine-1-yl)prop-2-yne-1-yl]anthracene: Synthesis and G-quadruplex Selectivity

G-quadruplex DNA is the target of several natural and synthetic small molecules with antiproliferative and antiviral activity. We here report the synthesis through <i>Sonogashira</i> reaction and A3 coupling of a disubstituted anthracene derivative, 9,10-bis[(4-(2-hydroxyethyl)piperazine-1-yl)prop-2...

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Autori principali: Giovanni Ribaudo, Alberto Ongaro, Erika Oselladore, Giuseppe Zagotto, Maurizio Memo, Alessandra Gianoncelli
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2020-05-01
Serie:Molbank
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Accesso online:https://www.mdpi.com/1422-8599/2020/2/M1138
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