Pro-excitatory alterations in sodium channel activity facilitate subiculum neuron hyperexcitability in temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is a common form of adult epilepsy involving the limbic structures of the temporal lobe. Subiculum neurons act to provide a major output from the hippocampus and consist of a large population of endogenously bursting excitatory neurons. In TLE, subiculum neurons are larg...

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Bibliografske podrobnosti

Principais autores:	Bryan S. Barker, Aradhya Nigam, Matteo Ottolini, Ronald P. Gaykema, Nicholas J. Hargus, Manoj K. Patel
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2017-12-01
Serija:	Neurobiology of Disease
Teme:	Subiculum Temporal lobe epilepsy Action potentials Sodium channels Electrophysiology Nav1.6
Online dostop:	http://www.sciencedirect.com/science/article/pii/S0969996117302061
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