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Effects of Chitosan Nanoparticles with Long Synthetic siRNAs Targeting VEGF in Triple-Negative Breast Cancer Cells

Abstract Vascular endothelial growth factor (VEGF) is an essential angiogenic factor in breast cancer development and metastasis. Small interfering RNAs (siRNAs) can specifically silence genes via the RNA interference pathway, therefore were investigated as cancer therapeutics. In this study, we inv...

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Main Authors: Birnur Cömez, Jülide Akbuğa
Format: Artigo
Language:Inglês
Published: Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2023-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
siRNA
VEGF
Chitosan
Nanoparticle
Breast cancer
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502023000100389&tlng=en
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