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Platelet Autophagy as a Druggable Intracellular Pathway: Therapeutic Opportunities in Thromboinflammatory Diseases

Platelet hyperreactivity is a central driver of thromboinflammatory diseases, including ischemic stroke, cardiovascular disorders, and autoimmune conditions. Current antiplatelet therapies primarily target surface receptors or coagulation pathways and are frequently limited by drug resistance, bleed...

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Principais autores: Ting-Lin Yen, Jing-Shiun Jan, Ruei-Dun Teng, Pi-Chan Ko, Rajeev Taliyan, Chih-Hao Yang, Jui-Ming Sun, Joen-Rong Sheu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-02-01
Serier:Pharmaceutics
Fag:
platelet autophagy
drug targeting
intracellular therapeutics
thromboinflammation
pharmacological modulation
precision medicine
Online adgang:https://www.mdpi.com/1999-4923/18/3/293
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