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Regional lung deflation with increased airway volume underlies the functional response to bronchodilators in chronic obstructive pulmonary disease

Abstract Bronchodilators, including long‐acting muscarinic antagonists (LAMAs), improve airflow limitation and lung hyperinflation in patients with chronic obstructive pulmonary disease (COPD). While bronchodilators increase airway caliber and deflate the lungs, little is known about the effects of...

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Principais autores: Naoya Tanabe, Susumu Sato, Shigeo Muro, Hiroshi Shima, Tsuyoshi Oguma, Kazuya Tanimura, Atsuyasu Sato, Toyohiro Hirai
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2019-12-01
coleção:Physiological Reports
Assuntos:
airway
bronchodilator
COPD
CT
hyperinflation
total airway count
Acesso em linha:https://doi.org/10.14814/phy2.14330
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