Assessing the impact of insulin resistance trajectories on cardiovascular disease risk using longitudinal targeted maximum likelihood estimation

Abstract Background Cardiovascular disease (CVD) is closely associated with Insulin Resistance (IR). However, there is limited research on the relationship between trajectories of IR and CVD incidence, considering both time-invariant and time-varying confounders. We employed advanced causal inferenc...

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Detalhes bibliográficos

Principais autores:	Yaning Feng, Liangying Yin, Haoran Huang, Yongheng Hu, Sitong Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-03-01
coleção:	Cardiovascular Diabetology
Assuntos:	Cardiovascular disease Insulin resistance TyG-BMI TyG index Longitudinal study Targeted maximum likelihood estimation
Acesso em linha:	https://doi.org/10.1186/s12933-025-02651-6
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