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Observing one-divalent-metal-ion-dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo

Metal-ion-dependent nucleases play crucial roles in cellular defense and biotechnological applications. Time-resolved crystallography has resolved catalytic details of metal-ion-dependent DNA hydrolysis and synthesis, uncovering the essential roles of multiple metal ions during catalysis. The histid...

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Váldodahkkit: Caleb Chang, Grace Zhou, Yang Gao
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: eLife Sciences Publications Ltd 2024-08-01
Ráidu:eLife
Fáttát:
Liŋkkat:https://elifesciences.org/articles/99960
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