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Type I Interferon Predicts an Alternate Immune System Phenotype in Systemic Lupus Erythematosus

Objective Type I interferon (IFN) is important to systemic lupus erythematosus (SLE) pathogenesis, but it is not clear how chronic elevations in IFN alter immune function. We compared cytokine responses after whole blood stimulation with Toll‐like receptor (TLR) agonists in high‐ and low‐IFN SLE pat...

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Autores principales: Uma Thanarajasingam, Anoohya N. Muppirala, Mark A. Jensen, Yogita Ghodke‐Puranik, Jessica M. Dorschner, Danielle M. Vsetecka, Shreyasee Amin, Ashima Makol, Floranne Ernste, Thomas Osborn, Kevin Moder, Vaidehi Chowdhary, Timothy B. Niewold
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2019-10-01
Colección:ACR Open Rheumatology
Acceso en línea:https://doi.org/10.1002/acr2.11073
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