Intravenous zoledronate for pediatric langerhans cell histiocytosis with bone involvement

Bone involvement in pediatric Langerhans cell histiocytosis (LCH) causes pain, functional impairment, and frequent relapse, creating a need for adjunctive therapies with rapid skeletal benefit. At National University Hospital, Singapore, a tertiary pediatric hematology-oncology referral centre, we r...

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Principais autores:	Jann Adriel Sy, Thuan Chong Quah, Pian Pian Tee, Cindy Wei Li Ho
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-04-01
Serija:	Frontiers in Pediatrics
Teme:	bisphosphonate therapy Langerhans cell histiocytosis pediatric bone lesions skeletal relapse zoledronate
Online dostop:	https://www.frontiersin.org/articles/10.3389/fped.2026.1825076/full
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