Extended genomic HLA typing identifies previously unrecognized mismatches in living kidney transplantation

IntroductionAntibody mediated rejection (ABMR) is the most common cause of long-term allograft loss in kidney transplantation (KT). Therefore, a low human leukocyte antigen (HLA) mismatch (MM) load is favorable for KT outcomes. Hitherto, serological or low-resolution molecular HLA typing have been a...

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Hlavní autoři:	Claudia Lehmann, Sarah Pehnke, Antje Weimann, Anette Bachmann, Katalin Dittrich, Friederike Petzold, Daniel Fürst, Jonathan de Fallois, Ramona Landgraf, Reinhard Henschler, Tom H. Lindner, Jan Halbritter, Ilias Doxiadis, Bernt Popp, Johannes Münch
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-01-01
Edice:	Frontiers in Immunology
Témata:	kidney transplantation HLA typing HLA mismatch donor specific antibodies NGS epitope matching
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1094862/full
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