Poor efficacy of the combination of clarithromycin, amikacin, and cefoxitin against Mycobacterium abscessus in the hollow fiber infection model

Abstract Background Mycobacterium abscessus (MABS) causes difficult-to-treat pulmonary and extra-pulmonary infections. A combination therapy comprising amikacin, cefoxitin, and a macrolide agent is recommended, but its antimicrobial activity and clinical efficacy is uncertain. Inducible resistance t...

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Detalhes bibliográficos

Principais autores:	Etienne Vignaud, Sylvain Goutelle, Charlotte Genestet, Jérôme Guitton, Sabine Cohen, Chloé Bourg, Aurore Durand, Laura Lebouteiller, Albin Bernard, Caroline Richet, Oana Dumitrescu, Elisabeth Hodille
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-01-01
coleção:	Annals of Clinical Microbiology and Antimicrobials
Assuntos:	Mycobacterium abscessus Hollow-fiber system Hollow-fiber infection model Clarithromycin Amikacin Cefoxitin
Acesso em linha:	https://doi.org/10.1186/s12941-025-00776-w
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