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ROS impairs tumor vasculature normalization through an endocytosis effect of caveolae on extracellular SPARC

Abstract Background The accumulation of reactive oxygen species (ROS) in tumor microenvironment (TME) is an important player for tumorigenesis and progression. We aimed to explore the outcomes of ROS on tumor vessels and the potential regulated mechanisms. Methods Exogenous H2O2 was adopted to simul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ye Zhao, Jing Yu, Ai Huang, Qin Yang, Guiling Li, Yong Yang, Yeshan Chen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2023-08-01
Cyfres:Cancer Cell International
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s12935-023-03003-8
Tagiau: Ychwanegu Tag
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