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The effects of N-acetylcysteine on cisplatin-induced cardiotoxicity on isolated rat hearts after short-term global ischemia

The aim of this study was to estimate the protective effect of N-acetyl-l-cysteine (NAC) against cisplatin-induced cardiotoxicity under conditions of ischemic-reperfusion injury. Wistar albino rats were randomly divided into three groups (n = 8): control, cisplatin (5 mg/kg/w, i.p., 5 weeks) and cis...

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主要な著者: Gvozden Rosic, Ivan Srejovic, Vladimir Zivkovic, Dragica Selakovic, Jovana Joksimovic, Vladimir Jakovljevic
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2015-01-01
シリーズ:Toxicology Reports
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2214750015300299
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