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Mitophagy and cGAS–STING crosstalk in neuroinflammation

Mitophagy, essential for mitochondrial health, selectively degrades damaged mitochondria. It is intricately linked to the cGAS–STING pathway, which is crucial for innate immunity. This pathway responds to mitochondrial DNA and is associated with cellular stress response. Our review explores the mole...

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Gardado en:
Principais autores: Xiaogang Zhou, Jing Wang, Lu Yu, Gan Qiao, Dalian Qin, Betty Yuen-Kwan Law, Fang Ren, Jianming Wu, Anguo Wu
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2024-08-01
Series:Acta Pharmaceutica Sinica B
Assuntos:
Neuroinflammation
Mitophagy
cGAS–STING
Innate immunity
Mitochondrial DNA
Crosstalk
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2211383524001904
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