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Chondrocyte Homeostasis and Differentiation: Transcriptional Control and Signaling in Healthy and Osteoarthritic Conditions

Chondrocytes are the main cell type in articular cartilage. They are embedded in an avascular, abundant, and specialized extracellular matrix (ECM). Chondrocytes are responsible for the synthesis and turnover of the ECM, in which the major macromolecular components are collagen, proteoglycans, and n...

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Main Authors: Yara M. Michelacci, Raquel Y. A. Baccarin, Nubia N. P. Rodrigues
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-06-01
Series:Life
Subjects:
chondrocyte transcription control
differentiation
apoptosis
osteoarthritis
chondroitin sulfate
Online Access:https://www.mdpi.com/2075-1729/13/7/1460
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