Validation of a Pseudovirus Neutralization Assay for Severe Acute Respiratory Syndrome Coronavirus 2 Omicron JN.1 and LP.8.1 Subvariant Lineage Strains with Homologous and Heterologous Matched Sera in Clinically Relevant Samples

The pseudovirus neutralization (PNT) assay is an established high-throughput, robust, and efficient BSL-2 method for detecting neutralizing antibodies (NAbs) against SARS-CoV-2 with the correlates of protection previously established for the ancestral (Wuhan) strain. The PNT assay was validated usin...

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Huvudupphov:	Zhaohui Cai, Raj Kalkeri, Benjamin Haner, Mi Wang, Paul Skonieczny, Bahar Osman, Dominic Dent, David Silva, Kevin Auerbach, Emmanuel Faust, Sheau-Line Feng, Miranda R. Cai, Mingzhu Zhu, Shane Cloney-Clark, Joyce S. Plested
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2026-05-01
Serie:	Microorganisms
Ämnen:	COVID-19 immunogenicity SARS-CoV-2 assay validation correlate of protection Omicron JN.1
Länkar:	https://www.mdpi.com/2076-2607/14/5/1042
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