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IL-32γ promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis

Abstract Background Interleukin 32 (IL-32) is a pro-inflammatory cytokine induced in patients with American tegumentary leishmaniasis (ATL) caused by Leishmania braziliensis. Here, we investigated whether IL-32 is also expressed in patient lesions caused by L. amazonensis. In addition, we evaluated...

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Auteurs principaux: Rodrigo Saar Gomes, Muriel Vilela Teodoro Silva, Jéssica Cristina dos Santos, Lucas Luiz de Lima Silva, Aline Carvalho Batista, Juliana Reis Machado, Mauro Martins Teixeira, Miriam Leandro Dorta, Milton Adriano Pelli de Oliveira, Charles A Dinarello, Leo A. B. Joosten, Fátima Ribeiro-Dias
Format: Artigo
Langue:Inglês
Publié: BMC 2017-07-01
Collection:Parasites & Vectors
Sujets:
Leishmania amazonensis
Leishmania braziliensis
Cutaneous leishmaniasis
IL-32
Cytokines
Mouse model
Accès en ligne:http://link.springer.com/article/10.1186/s13071-017-2268-4
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